Saizen 8 mg (24 IU) is used to treat children with hormonal disturbances leading to in growth delay and adults suffering from hormone deficiency. Saizen? is produced by a mammalian cell line (mouse C127) that has been modified by the addition of the human growth hormone gene. Saizen?, with the correct three-dimensional configuration, is secreted directly through the cell membrane into the cell-culture medium for collection and purification. Saizen? is a highly purified preparation.